Sorin Lab News
Sorin Lab alumus Amethyst Radcliffe was recently featured in the APS Newsletter for her work on thin films at PPG Aerospace
Sorin Lab System Administrator/Computer Science major Xavier Martinez was recently inducted into the RISE program
Lab alumnus Analisa Garcia has completed her Undergraduate Honors Thesis and is heading for USC Pharmacy School in Fall 2016
Sorin Lab researcher and Chemical Engineering major Angela Choy received a 2016 Boeing Academic Scholarship
Biochemistry/Physics double major Yessica Gomez was awarded a 2016 Women & Philanthropy Research Scholarship
Biochemistry major Sean McCoy graduated with Department Honors and received the AIC Biochemist of the Year award
MS Physics major Walter Alvarado won Best Graduate Student Poster at the 2015 Far West meeting of the American Physical Society
Biochem major Ji Won Lee graduated with Dept Honors and received the 2015 AIC Biochemist of the Year award
Sorin Lab biochemistry major Khai Nguyen was awarded the 2015 Hypercube Award for computational chemistry
Biochemistry major Dakota Rochelle received a 2015 Women & Philanthropy Scholarship to support his research in RNA folding
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Computational Biochemistry & Biophysics
Members of the Sorin Lab study the structure and dynamics of biological molecules via computer modeling and simulation.
Using cluster computing and the Folding@Home Distributed Computing Project, we can apply a variety of models and
methods to sample large numbers of independent simulations. Indeed, we are now capable of simulating some molecular events
in dynamic equilibrium, making simulation a powerful tool with which to probe topics in molecular biology and biophysics,
including molecular recognition and drug design, RNA and protein folding, and many other processes.
Ensemble Molecular Dynamics of a Protein-Ligand Complex: Residual Inhibitor Entropy Enhances Drug Potency in ButyrylcholinesteraseEric J Sorin, Walter Alvarado, Samantha Cao, Amethyst Radcliffe, Phuc La & Yi An (2017). Bioenergetics 6(1), DOI:10.4172/2167-7662.1000145.
The Extent of Pyrene Excimer Fluorescence Emission Is a Reflector of Distance and Flexibility: Analysis of the Segment Linking the LDL Receptor-Binding and Tetramerization Domains of Apolipoprotein E3Gursharan K. Bains, Sea H. Kim, Eric J. Sorin, & Vasanthy Narayanaswami (2012). Biochemistry 51, 6207-6219.
Evaluating molecular mechanical potentials for helical peptides and
Erik J. Thompson*, Allison J. DePaul*, Sarav Patel*, & Eric J. Sorin (2010). PLoS One, 5, e10056, doi:10.1371/journal.pone.0010056.